Tyr-Gly-Gly-Phe-Met-OH

• CAT Number: I004188
• CAS Number: 58569-55-4
• Molecular Formula: C27H35N5O7S
• Molecular Weight: 573.66
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: DMSO: ≥ 40 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid
• InChI: InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1
• InChIKey: YFGBQHOOROIVKG-FKBYEOEOSA-N
• SMILES: CSCCC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N

Tyr-Gly-Gly-Phe-Met-OH（Cat No.:I004188） is a peptide sequence that has been found to regulate human immune function and exhibit anti-tumor effects. It acts by binding to opioid receptors, specifically the delta-opioid receptor subtype. Activation of these receptors can modulate immune responses and exert anti-inflammatory effects. Additionally, binding to opioid receptors may contribute to the inhibition of tumor growth. Further research is necessary to fully understand the mechanisms and potential therapeutic applications of Tyr-Gly-Gly-Phe-Met-OH in immune regulation and cancer treatment.

Reference

[1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.