Tyrosinase-IN-12

• CAT Number: I040797
• CAS Number: 1860779-42-5
• Molecular Formula: C16H12ClN3S
• Molecular Weight: 313.80
• Purity: ≥95%
• Synonyms: N-[(E)-(4-chlorophenyl)methylideneamino]-4-phenyl-1,3-thiazol-2-amine
• InChI: InChI=1S/C16H12ClN3S/c17-14-8-6-12(7-9-14)10-18-20-16-19-15(11-21-16)13-4-2-1-3-5-13/h1-11H,(H,19,20)/b18-10+
• InChIKey: YQKYELGBAMTOTP-VCHYOVAHSA-N
• SMILES: C1=CC=C(C=C1)C2=CSC(=N2)NN=CC3=CC=C(C=C3)Cl

Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors[1].
Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) (3day) is a potential anti-browning agent for fresh-cut fruits and vegetables[1].

Reference

[1]. Djafarou S, et al. Synthesis and evaluation of the antioxidant and anti-tyrosinase activities of thiazolyl hydrazone derivatives and their application in the anti-browning of fresh-cut potato. Food Chem.