Tyrphostin AG 112

For research use only. Not for therapeutic Use.

  • CAT Number: M135462
  • CAS Number: 144978-82-5
  • Molecular Formula: C13H8N4O
  • Molecular Weight: 236.23
  • Purity: ≥95%
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Tyrphostin AG 112 is an EGFR phosphorylation inhibitor[1].


Catalog Number M135462
CAS Number 144978-82-5
Synonyms

(3Z)-2-amino-4-(4-hydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile

Molecular Formula C13H8N4O
Purity ≥95%
InChI InChI=1S/C13H8N4O/c14-6-10(13(17)11(7-15)8-16)5-9-1-3-12(18)4-2-9/h1-5,18H,17H2/b10-5+
InChIKey DXVJRTIPBNBLLB-BJMVGYQFSA-N
SMILES C1=CC(=CC=C1C=C(C#N)C(=C(C#N)C#N)N)O
Reference

[1]. Rodrigo Franco, et al. Epidermal Growth Factor Receptor Is Activated by Hyposmolarity and Is an Early Signal Modulating Osmolyte Efflux Pathways in Swiss 3T3 Fibroblasts. Pflugers Arch. 2004 Mar;447(6):830-9.
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