For research use only. Not for therapeutic Use.
Tyrphostin AG 112 is an EGFR phosphorylation inhibitor[1].
Catalog Number | M135462 |
CAS Number | 144978-82-5 |
Synonyms | (3Z)-2-amino-4-(4-hydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile |
Molecular Formula | C13H8N4O |
Purity | ≥95% |
InChI | InChI=1S/C13H8N4O/c14-6-10(13(17)11(7-15)8-16)5-9-1-3-12(18)4-2-9/h1-5,18H,17H2/b10-5+ |
InChIKey | DXVJRTIPBNBLLB-BJMVGYQFSA-N |
SMILES | C1=CC(=CC=C1C=C(C#N)C(=C(C#N)C#N)N)O |
Reference | [1]. Rodrigo Franco, et al. Epidermal Growth Factor Receptor Is Activated by Hyposmolarity and Is an Early Signal Modulating Osmolyte Efflux Pathways in Swiss 3T3 Fibroblasts. Pflugers Arch. 2004 Mar;447(6):830-9. |