U-18666A

• CAT Number: I010437
• CAS Number: 3039-71-2
• Molecular Formula: C25H42ClNO2
• Molecular Weight: 424.06
• Purity: ≥95%
• Synonyms: (3β)-3-[2-(Diethylamino)ethoxy]androst-5-en-17-one hydrochloride
• Target: Dengue virus
• Solubility: Soluble to 100 mM in water
• Storage: 2-8°C
• IUPAC Name: (3S,8R,9S,10R,13S,14S)-3-[2-(diethylamino)ethoxy]-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one;hydrochloride
• InChI: InChI=1S/C25H41NO2.ClH/c1-5-26(6-2)15-16-28-19-11-13-24(3)18(17-19)7-8-20-21-9-10-23(27)25(21,4)14-12-22(20)24;/h7,19-22H,5-6,8-17H2,1-4H3;1H/t19-,20-,21-,22-,24-,25-;/m0./s1
• InChIKey: GZFYZYBWLCYBMI-MYZJJQSMSA-N
• SMILES: CCN(CC)CCO[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CCC4=O)C)C.Cl

U-18666A（Cat No.:I010437）is a high-purity sterol transport inhibitor widely used in biochemical and pharmacological research. It blocks cholesterol trafficking within cells by targeting the late endosomal/lysosomal pathway, making it an essential tool for studying Niemann-Pick disease type C and cholesterol metabolism. U-18666A is also utilized in exploring lipid storage disorders, viral entry mechanisms, and autophagy. Its ability to induce intracellular cholesterol accumulation provides insights into cellular lipid regulation and disease pathology.