For research use only. Not for therapeutic Use.
Selective nonpeptide kappa-Opioid receptor agonist, which has been found to stimulate the release of adrenocorticotropin (acth) via the release of hypothalmic arginine vasopressin and corticotropin releasing factor
| CAS Number | 67197-96-0 |
| Molecular Formula | C19H26Cl2N2O.HCl |
| Purity | ≥95% |
| IUPAC Name | 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide;hydrochloride |
| InChI | InChI=1S/C19H26Cl2N2O.ClH/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H/t17-,18-;/m1./s1 |
| SMILES | CN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.Cl |
| Reference | ML Laorden et al. Effects of U-50,488H and U-50,488H withdrawal on c-fosexpression in the rat paraventricular nucleus. Correlation with c-fos in brainstem catecholaminergic neurons. Br. J. Pharmacol. 2003, 138, 1544–1552. |
