For research use only. Not for therapeutic Use.
U-<wbr></wbr>74389G is an antioxidant which prevents iron-<wbr></wbr>dependent lipid peroxidation. It protects against ischemia-<wbr></wbr>reperfusion injury in animal heart, liver, and kidney models.
| Catalog Number | R067369 |
| CAS Number | 153190-29-5 |
| Synonyms | Methylated Tirilazad |
| Molecular Formula | C37H50N6O2 • C4H4O4 |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C37H50N6O2.C4H4O4/c1-36-13-11-27(44)23-26(36)7-8-28-29-9-10-31(37(29,2)14-12-30(28)36)32(45)25-40-19-21-42(22-20-40)34-24-33(41-15-3-4-16-41)38-35(39-34)43-17-5-6-18-43;5-3(6)1-2-4(7)8/h11-13,23-24,28-29,31H,3-10,14-22,25H2,1-2H3;1-2H,(H,5,6 |
| InChIKey | ABCSSKWSUJMJCP-WQDFMEOSSA-N |
| SMILES | C[C@@]12[C@](CC[C@@H]2C(CN3CCN(C4=CC(N5CCCC5)=NC(N6CCCC6)=N4)CC3)=O)([H])[C@](C7=CC1)([H])CCC([C@]7(C)C=C8)=CC8=O.OC(/C=CC(O)=O)=O |
| Reference | 1.Ishizaki, N.,Zhu, Y.,Zhang, S., et al. Comparison of various lazaroid compounds for protection against ischemic liver injury. Transplantation 63, 202-208 (1997). |
