For research use only. Not for therapeutic Use.
U-<wbr></wbr>75302 is an LTB<sub>4</sub> receptor antagonist with a K<sub>i</sub> of 159 nM on guinea pig lung membranes. This activity is specific for the BLT<sub>1</sub> receptor; U-<wbr></wbr>75302 does not antagonize the binding of [
| Catalog Number | R067354 |
| CAS Number | 119477-85-9 |
| Synonyms | 6-(6-(3R-hydroxy-1E,5Z-undecadien-1-yl)-2-pyridinyl)-1,5S-hexanediol |
| Molecular Formula | C22H35NO3 |
| Purity | ≥95% |
| Target | Leukotriene Receptor |
| Storage | -20°C |
| InChI | InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-13-21(25)16-15-19-11-10-12-20(23-19)18-22(26)14-8-9-17-24/h6-7,10-12,15-16,21-22,24-26H,2-5,8-9,13-14,17-18H2,1H3/b7-6-,16-15+/t21-,22+/m1/s1 |
| InChIKey | JNBOAUIJLDEICX-LJCAKPRGSA-N |
| SMILES | OCCCC[C@H](O)CC1=NC(/C=C/[C@H](O)C/C=CCCCCC)=CC=C1 |
| Reference | 1.Falcone, R.C., and Aharony, D. Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents. Journal of Pharmacology and Experimental Therapeutics 255, 565-571 (1990). |
