For research use only. Not for therapeutic Use.
Selective orally active 5-HT1A full agonist with high intrinsic activity
| Catalog Number | I047516 |
| CAS Number | 149654-41-1 |
| Molecular Formula | C19H25N3.HCl |
| Purity | ≥95% |
| IUPAC Name | (8R)-8-(dipropylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-2-carbonitrile;hydrochloride |
| InChI | InChI=1S/C19H25N3.ClH/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19;/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3;1H/t16-;/m1./s1 |
| SMILES | CCCN(CCC)[C@@H]1CCC2=C(C1)C3=C(C=C2)NC(=C3)C#N.Cl |
| Reference | RB McCall et al. Characterization of U-92016A as a selective, orally active, high intrinsic activity 5-hydroxytryptamine1A agonist. J. Pharmacol. Exp. Ther. 1994, 271(2), 875-883.
AG Romero et al. Novel 2-substituted tetrahydro-3H-benz[e]indolamines: highly potent and selective agonists acting at the 5-HT1A receptor as possible anxiolytics and antidepressants. J. Med. Chem. 1993, 36(15), 2066–2074. |
