U-93631

• CAT Number: I001890
• CAS Number: 152273-12-6
• Molecular Formula: C₁₇H₂₁N₃O₂
• Molecular Weight: 299.37
• Purity: ≥95%
• Synonyms: tert-butyl 4,4-dimethyl-4,5-dihydroimidazo[1,5-a]quinoxaline-3-carboxylate
• Target: Neuronal Signaling
• Solubility: DMSO ≥ 34 mg/mL
• Storage: Store at RT
• InChI: InChI=1S/C17H21N3O2/c1-16(2,3)22-15(21)13-14-17(4,5)19-11-8-6-7-9-12(11)20(14)10-18-13/h6-10,19H,1-5H3
• InChIKey: NXBSEJKZKXIYMD-UHFFFAOYSA-N
• SMILES: CC1(C2=C(N=CN2C3=CC=CC=C3N1)C(=O)OC(C)(C)C)C

U-93631 (CAT: I001890) is a ligand that interacts with the GABAA receptor, a type of receptor involved in inhibitory neurotransmission in the central nervous system. It possesses a unique chemical structure that distinguishes it from other known ligands. GABAA receptors are ion channels that respond to the neurotransmitter gamma-aminobutyric acid (GABA), and their modulation can influence neuronal activity and excitability. By binding to the GABAA receptor, U-93631 may modulate GABAergic signaling and affect inhibitory processes in the brain.

Reference

[1]. Dillon,GH et al.U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A receptors.Molecular Pharmacology October 1993, 44 (4) 860-865