For research use only. Not for therapeutic Use.
UAA crosslinker 1 hydrochloride (Cat.No:I020104) is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases[1].
| Catalog Number | I020104 |
| CAS Number | 1167421-25-1 |
| Molecular Formula | C₉H₁₇N₅O₄ |
| Purity | ≥95% |
| Target | Azide |
| Reference | [1]. VanBrunt MP, et al. Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry. Bioconjug Chem. 2015 Nov 18;26(11):2249-60. |
