UAMC 00039 dihydrochloride

• CAT Number: I011060
• CAS Number: 697797-51-6
• Molecular Formula: C16H24ClN3O • 2HCl
• Molecular Weight: 382.8
• Purity: ≥95%
• Synonyms: (2S)-2-Amino-4-[[(4-chlorophenyl)methyl]amino]-1-(1-piperidinyl)-1-butanone dihydrochloride
• Target: Dipeptidyl Peptidase
• Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
• Storage: Store at -20C
• InChIKey: IWXMOQGMIWZNPR-CKUXDGONSA-N

UAMC 00039 dihydrochloride (CAT: I011060) is a potent inhibitor of dipeptidyl peptidase II (DPP-II) with an IC50 value of 0.48 nM. It exhibits selectivity for DPP-II over other dipeptidyl peptidases such as DPP-9, DPP-8, and DPP-IV, with IC50 values of 78.6 μM, 142 μM, and 165 μM, respectively. By specifically targeting DPP-II, UAMC 00039 dihydrochloride has the potential to modulate peptide metabolism and impact various physiological and pathological processes. Its selective inhibitory activity against DPP-II makes it a valuable tool for studying DPP-II function and a potential therapeutic agent in DPP-II-related pathways.