For research use only. Not for therapeutic Use.
UAMC-3203 is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
No toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks)[1].
| Catalog Number | I019337 |
| CAS Number | 2271358-64-4 |
| Synonyms | 3-(benzylamino)-4-(cyclohexylamino)-N-(2-piperazin-1-ylethyl)benzenesulfonamide |
| Molecular Formula | C25H37N5O2S |
| Purity | ≥95% |
| InChI | InChI=1S/C25H37N5O2S/c31-33(32,28-15-18-30-16-13-26-14-17-30)23-11-12-24(29-22-9-5-2-6-10-22)25(19-23)27-20-21-7-3-1-4-8-21/h1,3-4,7-8,11-12,19,22,26-29H,2,5-6,9-10,13-18,20H2 |
| InChIKey | HSYSVXKJIVUNBR-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)NC2=C(C=C(C=C2)S(=O)(=O)NCCN3CCNCC3)NCC4=CC=CC=C4 |
| Reference | [1]. Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140. |
