UBA5-IN-1

• CAT Number: I042635
• CAS Number: 1831169-11-9
• Molecular Formula: C26H40F6N10O11S2Zn
• Molecular Weight: 912.16
• Purity: ≥95%
• Synonyms: zinc;(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-N-[6-oxo-6-(1,4,7,10-tetrazacyclododec-1-yl)hexyl]oxolane-2-carboxamide;trifluoromethanesulfonate
• InChI: InChI=1S/C24H40N10O5.2CHF3O3S.Zn/c25-21-17-22(31-14-30-21)34(15-32-17)24-19(37)18(36)20(39-24)23(38)29-5-3-1-2-4-16(35)33-12-10-27-8-6-26-7-9-28-11-13-33;2*2-1(3,4)8(5,6)7;/h14-15,18-20,24,26-28,36-37H,1-13H2,(H,29,38)(H2,25,30,31);2*(H,5,6,7);/q;;;+2/p-2/t18-,19+,20-,24+;;;/m0.../s1
• InChIKey: DLPRYIVGTKSVTR-WAYDLRBYSA-L
• SMILES: C1CNCCN(CCNCCN1)C(=O)CCCCCNC(=O)[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O.C(F)(F)(F)S(=O)(=O)[O-].C(F)(F)(F)S(=O)(=O)[O-].[Zn+2]

UBA5-IN-1（Cat No.:I042635）is a selective inhibitor targeting UBA5 (Ubiquitin-like modifier activating enzyme 5), an enzyme involved in the activation of ubiquitin-like proteins that regulate various cellular processes. UBA5 plays a key role in protein homeostasis, including the modulation of protein degradation pathways. By inhibiting UBA5, UBA5-IN-1 disrupts cellular protein modifications and may help target diseases where protein regulation is impaired, such as cancer and neurodegenerative disorders. This compound is being explored for its potential to modulate cellular processes, offering new therapeutic strategies in diseases with dysregulated protein function.