UBP301 hydrochloride

• CAT Number: I041382
• Molecular Formula: C15H15ClIN3O6
• Molecular Weight: 495.65
• Purity: ≥95%
• Synonyms: 4-[[3-[(2S)-2-amino-2-carboxyethyl]-5-iodo-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid;hydrochloride
• InChI: InChI=1S/C15H14IN3O6.ClH/c16-10-6-18(7-11(17)14(23)24)15(25)19(12(10)20)5-8-1-3-9(4-2-8)13(21)22;/h1-4,6,11H,5,7,17H2,(H,21,22)(H,23,24);1H/t11-;/m0./s1
• InChIKey: SDDGQKMHQXTCMN-MERQFXBCSA-N
• SMILES: C1=CC(=CC=C1CN2C(=O)C(=CN(C2=O)C[C@@H](C(=O)O)N)I)C(=O)O.Cl

UBP301 hydrochloride（Cat No.:I041382）is a potent and selective inhibitor of the ubiquitin-specific protease 30 (USP30), an enzyme involved in regulating the ubiquitin-proteasome system, which is crucial for maintaining cellular homeostasis. By inhibiting USP30, UBP301 hydrochloride modulates the degradation of specific proteins, influencing various cellular processes, including mitochondrial function and neurodegenerative diseases. It has shown promise in preclinical studies as a potential therapeutic agent for conditions such as Parkinson’s disease and other disorders associated with protein accumulation. The hydrochloride salt form enhances the compound’s stability and solubility, making it suitable for laboratory research.