For research use only. Not for therapeutic Use.
UCB9608 (Cat No.:I019608) is a potent and selective orally bioavailable inhibitor of PI4KIIIβ with IC50 of 11 nM. UCB9608 is a potent immunosuppressant with improved metabolic stability and exhibits excellent pharmacokinetic properties. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.
| Catalog Number | I019608 |
| CAS Number | 1616413-96-7 |
| Molecular Formula | C₂₀H₂₆N₈O₂ |
| Purity | ≥95% |
| Target | PI4K |
| Storage | Store at -20°C |
| IUPAC Name | (3S)-4-(6-amino-1-methylpyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methylpiperazine-1-carboxamide |
| InChI | InChI=1S/C20H26N8O2/c1-12-9-14(30-4)5-6-16(12)23-20(29)27-7-8-28(13(2)11-27)18-15-10-22-26(3)17(15)24-19(21)25-18/h5-6,9-10,13H,7-8,11H2,1-4H3,(H,23,29)(H2,21,24,25)/t13-/m0/s1 |
| InChIKey | WRONAJQPZWDYAR-ZDUSSCGKSA-N |
| SMILES | CC1CN(CCN1C2=NC(=NC3=C2C=NN3C)N)C(=O)NC4=C(C=C(C=C4)OC)C |
| Reference | [1]. Reuberson J, et al. Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo. J Med Chem. 2018 Aug 9;61(15):6705-6723. |
