For research use only. Not for therapeutic Use.
UCL-TRO-1938(CAT: I040899) is a potent allosteric activator of PI3Kα, with an EC50 value of approximately 60 μM. By activating PI3Kα, this compound enhances downstream signaling pathways involved in cell growth, survival, and metabolism. UCL-TRO-1938 has shown potential in inducing cell proliferation and exhibiting cardioprotective effects, which may help in heart-related conditions such as ischemic injury. Additionally, it has demonstrated neural regeneration properties, suggesting its relevance for neurodegenerative diseases. UCL-TRO-1938 can be used in research for Neurological Disease Research, Cardiovascular Disease Research, and exploring regenerative therapies.
| CAS Number | 2919575-27-0 |
| Synonyms | 1-[7-[[2-[4-(4-ethylpiperazin-1-yl)anilino]pyridin-4-yl]amino]-2,3-dihydroindol-1-yl]ethanone |
| Molecular Formula | C27H32N6O |
| Purity | ≥95% |
| IUPAC Name | 1-[7-[[2-[4-(4-ethylpiperazin-1-yl)anilino]pyridin-4-yl]amino]-2,3-dihydroindol-1-yl]ethanone |
| InChI | InChI=1S/C27H32N6O/c1-3-31-15-17-32(18-16-31)24-9-7-22(8-10-24)30-26-19-23(11-13-28-26)29-25-6-4-5-21-12-14-33(20(2)34)27(21)25/h4-11,13,19H,3,12,14-18H2,1-2H3,(H2,28,29,30) |
| InChIKey | RPOHONUDGBSZDK-UHFFFAOYSA-N |
| SMILES | CCN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=CC(=C3)NC4=CC=CC5=C4N(CC5)C(=O)C |
