For research use only. Not for therapeutic Use.
UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].
UCM 608 is a high affinity melatonin membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4 [1].
| Catalog Number | M101261 |
| CAS Number | 151889-03-1 |
| Synonyms | N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide |
| Molecular Formula | C19H20N2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) |
| InChIKey | OFCLARYYBGKCHN-UHFFFAOYSA-N |
| SMILES | CC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3 |
| Reference | [1]. Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45. [2]. Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057. |
