For research use only. Not for therapeutic Use.
UCSF648 is the inactive control probe for the 5-HT5A receptor partial agonist UCSF678 (Axon 3636) and the 5-HT1A/5-HT2B/5-HT7A receptor ligand UCSF686 (Axon 3635). UCSF648 showed no measurable effect on any of the 5-HT receptor subtypes.
KEYWORDS: UCSF648 dihydrochloride | Supplier | 5-HT5A receptor negative control | 5A6-48 | UCSF 648 | UCSF-648 | CAS [2248852-19-7] | Serotonin | 5-HT5A | Probe | Receptors
| Catalog Number | I047685 |
| CAS Number | 2248852-19-7 |
| Molecular Formula | C14H19N3O2S.2HCl |
| Purity | ≥95% |
| IUPAC Name | N,N-dimethyl-2-(quinolin-5-ylmethylamino)ethanesulfonamide |
| InChI | InChI=1S/C14H19N3O2S/c1-17(2)20(18,19)10-9-15-11-12-5-3-7-14-13(12)6-4-8-16-14/h3-8,15H,9-11H2,1-2H3 |
| SMILES | CN(C)S(=O)(=O)CCNCC1=C2C=CC=NC2=CC=C1 |
| Reference | KA Levit et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022 Mar 10;65(5):4201-4217. |
