UK 370106

For research use only. Not for therapeutic Use.

  • CAT Number: R014697
  • CAS Number: 230961-21-4
  • Molecular Formula: C35H44N2O5
  • Molecular Weight: 572.746
  • Purity: ≥95%
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UK 370106 is a highly selective inhibitor of MMP-3 and MMP-12 with IC50 values of 23 nM and 42 nM, respectively.


CAS Number 230961-21-4
Synonyms

(βR)-β-[[[(1S)-1-[[[(1S)-2-Methoxy-1-phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-2-methyl-[1,1’-biphenyl]-4-hexanoic Acid; (R)-3-(((S)-1-(((S)-2-Methoxy-1-phenylethyl)amino)-4,4-dimethyl-1-oxopentan-2-yl)carbamoyl)-6-(2-methyl-[1,1

Molecular Formula C35H44N2O5
Purity ≥95%
Target MMP
Solubility Soluble in DMSO > 10 mM
Storage Store at 4°C
IUPAC Name (3R)-3-[[(2S)-1-[[(1S)-2-methoxy-1-phenylethyl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl]-6-(3-methyl-4-phenylphenyl)hexanoic acid
InChI InChI=1S/C35H44N2O5/c1-24-21-25(19-20-29(24)26-14-8-6-9-15-26)13-12-18-28(22-31(38)39)33(40)37-32(35(2,3)4)34(41)36-30(23-42-5)27-16-10-7-11-17-27/h6-11,14-17,19-21,28,30,32H,12-13,18,22-23H2,1-5H3,(H,36,41)(H,37,40)(H,38,39)/t28-,30-,32-/m1/s1
InChIKey NSMABJUGSNPHMN-BHYWQNONSA-N
SMILES CC1=C(C=CC(=C1)CCCC(CC(=O)O)C(=O)NC(C(=O)NC(COC)C2=CC=CC=C2)C(C)(C)C)C3=CC=CC=C3

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