For research use only. Not for therapeutic Use.
UK 88947 is a protease inhibitor.
| Catalog Number | I037814 |
| CAS Number | 137015-76-0 |
| Synonyms | UK 88947; UK-88947; UK88947; UK-88,947; UK 88,947; UK88,947; |
| Molecular Formula | C40H60ClN5O7 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (3S)-3-((S)-2-(1-aminocyclohexane-1-carboxamido)-3-phenylpropanamido)-4-(((2S,5R)-3-hydroxy-5-(isobutylcarbamoyl)-7-methyl-1-phenyloctan-2-yl)amino)-4-oxobutanoic acid hydrochloride |
| InChI | InChI=1S/C40H59N5O7.ClH/c1-26(2)20-30(36(49)42-25-27(3)4)23-34(46)31(21-28-14-8-5-9-15-28)43-38(51)33(24-35(47)48)44-37(50)32(22-29-16-10-6-11-17-29)45-39(52)40(41)18-12-7-13-19-40;/h5-6,8-11,14-17,26-27,30-34,46H,7,12-13,18-25,41H2,1-4H3,(H,42,49)(H,43,51)(H,44,50)(H,45,52)(H,47,48);1H/t30-,31+,32+,33+,34?;/m1./s1 |
| InChIKey | OSKPXYCTBWIRIE-YVITZFCESA-N |
| SMILES | O=C(O)C[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(O)C[C@H](C(NCC(C)C)=O)CC(C)C)=O)NC([C@H](CC2=CC=CC=C2)NC(C3(N)CCCCC3)=O)=O.[H]Cl |
| Reference | 1: Nagy K, Young M, Baboonian C, Merson J, Whittle P, Oroszlan S. Antiviral activity of human immunodeficiency virus type 1 protease inhibitors in a single cycle of infection: evidence for a role of protease in the early phase. J Virol. 1994 Feb;68(2):757-65. PubMed PMID: 8289379; PubMed Central PMCID: PMC236512. |
