For research use only. Not for therapeutic Use.
UK-88947 HCl(CAT: I037814) is a high-purity, potent inhibitor of matrix metalloproteinases (MMPs), specifically designed for research into extracellular matrix remodeling and related pathologies. This compound is widely used in studies focusing on cancer metastasis, angiogenesis, and inflammatory conditions, where MMP activity plays a critical role. With its selective inhibitory action, UK-88947 HCl helps elucidate the molecular mechanisms underlying tissue degradation and repair. Its stability and precision ensure reproducible results in biochemical and pharmacological studies, making it an essential tool for researchers investigating MMP-related therapeutic targets in oncology, cardiovascular health, and chronic inflammation.
Catalog Number | I037814 |
CAS Number | 137015-76-0 |
Synonyms | UK 88947; UK-88947; UK88947; UK-88,947; UK 88,947; UK88,947; |
Molecular Formula | C40H60ClN5O7 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | (3S)-3-((S)-2-(1-aminocyclohexane-1-carboxamido)-3-phenylpropanamido)-4-(((2S,5R)-3-hydroxy-5-(isobutylcarbamoyl)-7-methyl-1-phenyloctan-2-yl)amino)-4-oxobutanoic acid hydrochloride |
InChI | InChI=1S/C40H59N5O7.ClH/c1-26(2)20-30(36(49)42-25-27(3)4)23-34(46)31(21-28-14-8-5-9-15-28)43-38(51)33(24-35(47)48)44-37(50)32(22-29-16-10-6-11-17-29)45-39(52)40(41)18-12-7-13-19-40;/h5-6,8-11,14-17,26-27,30-34,46H,7,12-13,18-25,41H2,1-4H3,(H,42,49)(H,43,51)(H,44,50)(H,45,52)(H,47,48);1H/t30-,31+,32+,33+,34?;/m1./s1 |
InChIKey | OSKPXYCTBWIRIE-YVITZFCESA-N |
SMILES | O=C(O)C[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(O)C[C@H](C(NCC(C)C)=O)CC(C)C)=O)NC([C@H](CC2=CC=CC=C2)NC(C3(N)CCCCC3)=O)=O.[H]Cl |