For research use only. Not for therapeutic Use.
UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).
| Catalog Number | I011089 |
| CAS Number | 1426152-53-5 |
| Synonyms | 1-(1,2,3-benzothiadiazol-6-yl)-3-(2-oxo-2-piperidin-1-ylethyl)urea |
| Molecular Formula | C14H17N5O2S |
| Purity | ≥95% |
| InChI | InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21) |
| InChIKey | MYTRGTBDVGKKRO-UHFFFAOYSA-N |
| SMILES | C1CCN(CC1)C(=O)CNC(=O)NC2=CC3=C(C=C2)N=NS3 |
| Reference | [1]. Liu F, et al. Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J Med Chem. 2013 Mar 14;56(5):2110-24. |
