For research use only. Not for therapeutic Use.
UNC9512 is a potent methyl-lysine reader p53 binding protein 1 (53BP1) antagonist. UNC9512 can be used to study the role of 53BP1 in DNA repair, gene editing and tumorigenesis[1].
| Catalog Number | I040284 |
| CAS Number | 3032393-24-8 |
| Synonyms | (3S)-1-[4-(4-methylpiperazin-1-yl)pyridine-2-carbonyl]-N-[3-(3-oxo-1,2-dihydroisoindol-5-yl)phenyl]piperidine-3-carboxamide |
| Molecular Formula | C31H34N6O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C31H34N6O3/c1-35-12-14-36(15-13-35)26-9-10-32-28(18-26)31(40)37-11-3-5-24(20-37)29(38)34-25-6-2-4-21(16-25)22-7-8-23-19-33-30(39)27(23)17-22/h2,4,6-10,16-18,24H,3,5,11-15,19-20H2,1H3,(H,33,39)(H,34,38)/t24-/m0/s1 |
| InChIKey | OYWGFOXQBJYTIR-DEOSSOPVSA-N |
| SMILES | CN1CCN(CC1)C2=CC(=NC=C2)C(=O)N3CCCC(C3)C(=O)NC4=CC=CC(=C4)C5=CC6=C(CNC6=O)C=C5 |
| Reference | [1]. Devan J Shell, et al. Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen. J Med Chem. 2023 Oct 2. |
