URIC ACID SODIUM SALT

For research use only. Not for therapeutic Use.

  • CAT Number: M050750
  • CAS Number: 1198-77-2
  • Molecular Formula: C5H3N4O3 • Na
  • Molecular Weight: 190.1
  • Purity: ≥95%
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Uric acid is a ubiquitous end product of purine metabolism in humans that is mainly excreted in urine, whereas in other mammals it is further metabolized to allantoin by uricase. The final two steps in its production are catalyzed by xanthine oxidase, which generates superoxide. Uric acid acts as a potent peroxynitrite scavenger and antioxidant. However, high levels of serum uric acid (&gt;120 µg/ml), termed hyperuricemia, are associated with gout, kidney stones, metabolic syndrome, hypertension, renal disease, and cardiovascular disease. Uric acid in the form of monosodium urate crystals has been proposed to trigger interleukin-<wbr></wbr>1β-<wbr></wbr>mediated inflammation by activating the NOD-<wbr></wbr>like receptor protein 3 inflammasome.


CAS Number 1198-77-2
Synonyms

7,9-dihydro-1H-purine-2,6,8(3H)-trione, monosodium salt

Molecular Formula C5H3N4O3 • Na
Purity ≥95%
Target Immunology/Inflammation
Storage -20°C
InChIKey NAFSTSRULRIERK-UHFFFAOYSA-M

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