Uridine-[5’,5’-D2]

• CAT Number: R041435
• CAS Number: 82740-98-5
• Molecular Formula: C9H12N2O6
• Molecular Weight: 246.215
• Purity: ≥95%
• Synonyms: 1-β-D-Ribofuranosyluracil[5’,5’-D2]; β-Uridine[5’,5’-D2]; 1-β-D-Ribofuranosyluracil[5’,5’-D2]; 1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione[5’,5’-D2]; NSC 20256[5’,5’-D2]; β-Uridine[5’,5’-D2]
• Target: Cell Cycle/DNA Damage
• Storage: -20°C
• IUPAC Name: 1-[(2R,3R,4S,5R)-5-[dideuterio(hydroxy)methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione
• InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1/i3D2
• InChIKey: DRTQHJPVMGBUCF-APTDQHSTSA-N
• SMILES: [2H]C([2H])([C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=O)NC2=O)O)O)O

Uridine-[5’,5’-D2] is a deuterated form of uridine, with two deuterium atoms incorporated at the 5′ position of the ribose sugar. This isotopic labeling enhances its stability and allows for precise analysis using techniques such as NMR and mass spectrometry. The compound is crucial in biochemical and pharmaceutical research for studying nucleotide metabolism, RNA synthesis, and the role of uridine in cellular processes. In organic chemistry, Uridine-[5’,5’-D2] is used to investigate the behavior of nucleosides in chemical reactions and to track metabolic pathways. Its deuterium labeling is also valuable in understanding drug interactions and the impact of nucleoside analogs.