Usaramine

For research use only. Not for therapeutic Use.

  • CAT Number: M008863
  • CAS Number: 15503-87-4
  • Molecular Formula: C18H25NO6
  • Molecular Weight: 351.39
  • Purity: ≥95%
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Usaramine(Cat No.:M008863)is an indole alkaloid derived from plants in the Rauwolfia species, known for its biological activities, particularly in research related to neurological and cardiovascular systems. It has been studied for its potential effects on neurotransmitter regulation and receptor modulation, making it valuable in exploring treatments for disorders related to these pathways. While not commonly used therapeutically, Usaramine’s unique structure and pharmacological properties offer insight into natural compounds that influence neurological function. It serves as a useful tool in pharmacology for investigating plant-derived bioactive compounds.


Catalog Number M008863
CAS Number 15503-87-4
Synonyms

NISTC15503874;(15E)-12,18-Dihydroxysenecionan-11,16-dione;Usaramine;Mucronatine;(15E)-Retrorsine;trans-Retrorsine;Usaramin

Molecular Formula C18H25NO6
Purity ≥95%
Target Bacterial
Storage Store at -20°C
IUPAC Name (1R,4E,6R,7S,17R)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
InChI InChI=1S/C18H25NO6/c1-3-12-8-11(2)18(23,10-20)17(22)24-9-13-4-6-19-7-5-14(15(13)19)25-16(12)21/h3-4,11,14-15,20,23H,5-10H2,1-2H3/b12-3+/t11-,14-,15-,18-/m1/s1
InChIKey BCJMNZRQJAVDLD-FXGRWVCYSA-N
SMILES C/C=C/1\C[C@H]([C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1=O)(CO)O)C
Reference

1: Pieters LA, Vlietinck AJ. Spartioidine and Usaramine, Two Pyrrolizidine
Alkaloids from Senecio vulgaris. Planta Med. 1988 Apr;54(2):178-9. PubMed PMID:
17265238.
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2: Singh GB, Sharma ML, Ghatak BJ. Pharmacological investigations of usaramine,
an alkaloid isolated from Crotalaria brevifolia. Indian J Exp Biol. 1969
Jul;7(3):144-7. PubMed PMID: 5359068.

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