USP28-IN-4

• CAT Number: I041230
• CAS Number: 2931509-15-6
• Molecular Formula: C22H18Cl2N2O3S
• Molecular Weight: 461.36
• Purity: ≥95%
• Synonyms: 2-chloro-N-[4-chloro-3-(2,3-dihydro-1H-isoindol-5-yl)phenyl]-4-methylsulfonylbenzamide
• InChI: InChI=1S/C22H18Cl2N2O3S/c1-30(28,29)17-5-6-18(21(24)10-17)22(27)26-16-4-7-20(23)19(9-16)13-2-3-14-11-25-12-15(14)8-13/h2-10,25H,11-12H2,1H3,(H,26,27)
• InChIKey: FZNJOQKABIINMG-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC4=C(CNC4)C=C3)Cl

USP28-IN-4（Cat No.:I041230）is a small molecule inhibitor targeting the ubiquitin-specific protease 28 (USP28), a deubiquitinating enzyme involved in regulating cellular processes such as DNA repair, cell cycle progression, and apoptosis. By inhibiting USP28, this compound can potentially alter the stability of various proteins involved in cancer progression and other diseases. USP28-IN-4 is studied for its ability to modulate the ubiquitin-proteasome system, making it a promising tool in cancer research, as well as for therapeutic strategies targeting the regulation of protein degradation and cellular stress response.