UU-T02

• CAT Number: I037909
• CAS Number: 1500080-17-0
• Molecular Formula: C33H33ClN4O9
• Molecular Weight: 665.10
• Purity: 98%
• Synonyms: UU-T02; UU-T-02; UU-T 02; UUT02; UUT-02; UUT 02
• Target: β-catenin
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (4S)-4-[[(2S)-3-carboxy-2-[[(2S)-2-[[2-(5-chloro-1H-indol-2-yl)acetyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-5-methoxy-5-oxopentanoic acid
• InChI: InChI=1S/C33H33ClN4O9/c1-47-33(46)25(10-11-29(40)41)37-32(45)27(17-30(42)43)38-31(44)26(13-18-6-7-19-4-2-3-5-20(19)12-18)36-28(39)16-23-15-21-14-22(34)8-9-24(21)35-23/h2-9,12,14-15,25-27,35H,10-11,13,16-17H2,1H3,(H,36,39)(H,37,45)(H,38,44)(H,40,41)(H,42,43)/t25-,26-,27-/m0/s1
• InChIKey: SGTICZUBRHDIMI-QKDODKLFSA-N
• SMILES: COC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)CC3=CC4=C(N3)C=CC(=C4)Cl

UU-T02（Cat No.:I037909）is a small-molecule inhibitor designed to target and inhibit the protein Tyrosyl-tRNA synthetase (YARS), an enzyme involved in protein synthesis and cellular stress response. By inhibiting YARS, UU-T02 disrupts the translation process in cells, leading to a reduction in protein production and altered cellular metabolism. This compound has shown potential in preclinical studies for its ability to induce cell death in cancer cells and modulate immune responses. UU-T02 is being investigated for its therapeutic potential in cancer treatment and as a modulator of cellular stress pathways, particularly in tumorigenesis.