UVI 3003

• CAT Number: I010736
• CAS Number: 847239-17-2
• Molecular Formula: C28H36O4
• Molecular Weight: 436.59
• Purity: ≥95%
• Synonyms: 3-[4-Hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid
• Target: Retinoid X Receptors
• Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
• Storage: -20°C
• IUPAC Name: (E)-3-[4-hydroxy-3-(5,5,8,8-tetramethyl-3-pentoxy-6,7-dihydronaphthalen-2-yl)phenyl]prop-2-enoic acid
• InChI: InChI=1S/C28H36O4/c1-6-7-8-15-32-25-18-23-22(27(2,3)13-14-28(23,4)5)17-21(25)20-16-19(9-11-24(20)29)10-12-26(30)31/h9-12,16-18,29H,6-8,13-15H2,1-5H3,(H,30,31)/b12-10+
• InChIKey: APJSHECCIRQQDV-ZRDIBKRKSA-N
• SMILES: CCCCCOC1=CC2=C(C=C1C3=C(C=CC(=C3)/C=C/C(=O)O)O)C(CCC2(C)C)(C)C

UVI 3003（Cat No.:I010736）is a potent inhibitor of the enzyme NADPH oxidase, specifically targeting the NOX family of enzymes, which are responsible for producing reactive oxygen species (ROS) in cells. By inhibiting NADPH oxidase activity, UVI 3003 helps reduce oxidative stress, making it useful in research on diseases associated with excessive ROS production, such as cardiovascular diseases, neurodegenerative disorders, and certain cancers. Its selective action provides a reliable means for studying oxidative stress mechanisms, aiding in the development of novel therapies for ROS-related pathologies.