For research use only. Not for therapeutic Use.
UWA-101 (hydrochloride) (Item No. 15433) is an analytical reference material that is structurally categorized as an amphetamine. It inhibits both serotonin and dopamine reuptake (K<sub>i</sub>s = 467 and 894 nM, respectively), but has no effect on the reuptake of noradrenaline (K<sub>i</sub> > 50,000 nM). UWA-101 enhances L-DOPA anti-parkinsonian action without exacerbating dyskinesia. This product is intended for research and forensic applications.
| Catalog Number | R065046 |
| CAS Number | 1431520-52-3 |
| Synonyms | α-cyclopropyl-N-methyl-1,3-benzodioxole-5-ethanamine, monohydrochloride |
| Molecular Formula | C13H17NO2 • HCl |
| Purity | ≥95% |
| Target | Dopamine Transporter |
| Storage | -20°C |
| InChI | InChI=1S/C13H17NO2.ClH/c1-14-11(10-3-4-10)6-9-2-5-12-13(7-9)16-8-15-12;/h2,5,7,10-11,14H,3-4,6,8H2,1H3;1H |
| InChIKey | RTPDALMALRMSMM-UHFFFAOYSA-N |
| SMILES | CNC(C1CC1)CC2=CC(OCO3)=C3C=C2.Cl |
| Reference | 1.Johnston, T.H.,Millar, Z.,Huot, P., et al. A novel MDMA analogue, UWA-101, that lacks psychoactivity and cytotoxicity, enhances L-DOPA benefit in parkinsonian primates. The FASEB Journal 26(5), 2154-2163 (2012). |
