For research use only. Not for therapeutic Use.
VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM)[1].
| Catalog Number | I037928 |
| CAS Number | 1171341-19-7 |
| Synonyms | N-methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine;hydrochloride |
| Molecular Formula | C18H16ClN3S |
| Purity | ≥95% |
| InChI | InChI=1S/C18H15N3S.ClH/c1-19-18-21-15(11-22-18)16-13-9-5-6-10-14(13)20-17(16)12-7-3-2-4-8-12;/h2-11,20H,1H3,(H,19,21);1H |
| InChIKey | MMEANJJDNROSBC-UHFFFAOYSA-N |
| SMILES | CNC1=NC(=CS1)C2=C(NC3=CC=CC=C32)C4=CC=CC=C4.Cl |
| Reference | [1]. Latif R, et al. TSH Receptor Signaling Abrogation by a Novel Small Molecule. Front Endocrinol (Lausanne). 2016;7:130. Published 2016 Sep 27. |
