For research use only. Not for therapeutic Use.
Valencene (Cat No.:I018412) is a natural sesquiterpene found in citrus fruits, especially in Valencia oranges. It is a colorless liquid with a sweet, citrusy aroma, often used in the fragrance and flavor industries. Valencene has potential health benefits, including antioxidant and anti-inflammatory properties. It has been studied for its antimicrobial activity against certain pathogens, suggesting its use as a natural preservative or antimicrobial agent. Valencene is also used in the development of insect repellents due to its repellent properties against mosquitoes and other insects.
| CAS Number | 4630-07-3 |
| Molecular Formula | C₁₅H₂₄ |
| Purity | ≥95% |
| Target | NF-κB |
| Storage | 2-8°C |
| IUPAC Name | (3R,4aS,5R)-4a,5-dimethyl-3-prop-1-en-2-yl-2,3,4,5,6,7-hexahydro-1H-naphthalene |
| InChI | InChI=1S/C15H24/c1-11(2)13-8-9-14-7-5-6-12(3)15(14,4)10-13/h7,12-13H,1,5-6,8-10H2,2-4H3/t12-,13-,15+/m1/s1 |
| InChIKey | QEBNYNLSCGVZOH-NFAWXSAZSA-N |
| SMILES | CC1CCC=C2C1(CC(CC2)C(=C)C)C |
| Reference | [1]. Yang IJ, et al. Inhibitory Effect of Valencene on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. Evid Based Complement Alternat Med. 2016;2016:9370893.<br>[2]. Frohwitter J, et al. Production of the sesquiterpene (+)-valencene by metabolically engineered Corynebacterium glutamicum. J Biotechnol. 2014 Dec 10;191:205-13.<br>[3]. Marques FM, et al. In vitro anti-inflammatory activity of terpenes via suppression of superoxide and nitric oxide generation and the NF-κB signalling pathway. Inflammopharmacology. 2019 Apr;27(2):281-289. |
