(+)-Valerianol

• CAT Number: C000754
• CAS Number: 20489-45-6
• Molecular Formula: C₁₅H₂₆O
• Molecular Weight: 222.37
• Purity: ≥95%
• Synonyms: Kusenol; Kusunol; Valerianol; (2R,8R,8aS)-1,2,3,4,6,7,8,8a-Octahydro-α,α,8,8a-tetramethyl-2-naphthalenemethanol; 4βH,5α-Eremophil-1(10)-en-11-ol; [2R-(2α,8β,8aβ)]-1,2,3,4,6,7,8,8a-Octahydro-α,α,8,8a-tetramethyl-2-naphthalenemethanol
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Appearance: Colourless Oil
• Storage: 4°C
• IUPAC Name: 2-[(2R,8R,8aS)-8,8a-dimethyl-2,3,4,6,7,8-hexahydro-1H-naphthalen-2-yl]propan-2-ol
• InChI: InChI=1S/C15H26O/c1-11-6-5-7-12-8-9-13(14(2,3)16)10-15(11,12)4/h7,11,13,16H,5-6,8-10H2,1-4H3/t11-,13-,15+/m1/s1
• InChIKey: MQWIFDHBNGIVPO-KYOSRNDESA-N
• SMILES: CC1CCC=C2C1(CC(CC2)C(C)(C)O)C

(+)-Valerianol (Cat No.:C000754) is a natural sesquiterpenoid alcohol found in valerian root (Valeriana officinalis). It contributes to valerian’s sedative and anxiolytic properties, making it a potential candidate for herbal remedies targeting insomnia and anxiety. With its distinct chiral configuration, (+)-valerianol possesses specific pharmacological effects. Research suggests its involvement in modulating neurotransmitter systems, particularly GABAergic transmission, which contributes to its calming effects.

Reference

Kasaian, J., et al.: Pharm. Biol., 54, 2264-2268 (2016); Asadollahi-Baboli, M.: Int. J. Food Prop., 18, 597-607 (2015);