Valeryl salicylate

• CAT Number: I011557
• CAS Number: 64206-54-8
• Molecular Formula: C12H14O4
• Molecular Weight: 222.24
• Purity: ≥95%
• Synonyms: 2-pentanoyloxybenzoic acid
• InChI: InChI=1S/C12H14O4/c1-2-3-8-11(13)16-10-7-5-4-6-9(10)12(14)15/h4-7H,2-3,8H2,1H3,(H,14,15)
• InChIKey: WJHZBTMHUNVIKC-UHFFFAOYSA-N
• SMILES: CCCCC(=O)OC1=CC=CC=C1C(=O)O

Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1].
Valeryl salicylate (3, 10, 30 mg/kg; i.p.) shows anti-inflammatory effect in arachidonic acid (HY-109590)-induced ear oedema and Carrageenan (HY-125474)-induced paw oedema[1].

Reference

[1]. Siqueira-Junior JM, et al. Effects of valeryl salicylate, a COX-1 inhibitor, on models of acute inflammation in mice. Pharmacol Res. 2003 Nov;48(5):437-43.
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