Valsartan-d8

• CAT Number: S000313
• CAS Number: 1089736-72-0
• Molecular Formula: C24H21D8N5O3
• Molecular Weight: 443.57
• Purity: ≥95%
• IUPAC Name: (2S)-2,3,4,4,4-pentadeuterio-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-(trideuteriomethyl)butanoic acid
• InChI: InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1/i2D3,3D3,16D,22D
• InChIKey: ACWBQPMHZXGDFX-KFWZLTATSA-N
• SMILES: CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O

Valsartan-d8（Cat No.:S000313） is a deuterated form of valsartan, where eight hydrogen atoms are replaced with deuterium, improving its molecular stability. This alteration makes it highly valuable as an internal standard for precise analytical measurements in mass spectrometry and NMR spectroscopy techniques. Valsartan is an angiotensin II receptor antagonist commonly used to treat hypertension and heart failure. By integrating deuterium, valsartan-d8 facilitates more accurate investigations into the drug’s pharmacokinetics, enabling researchers to trace and analyze its absorption, distribution, metabolism, and excretion with enhanced clarity and detail.