For research use only, not for therapeutic use.
Vancomycin HCl is a bactericidal glycopeptide antibiotic and has been used to treat infections caused by multi drug resistant bacteria including methicillin resistant <em>Staphylococcus aureus</em> (MRSA).</br>Vancomycin prevents peptidoglycan synthesis by two separate mechanisms. One mechanism prevents N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) from linking together forming the peptidoglycan backbone. The second mechanism prevents crosslinking between amino acid residues in the peptidoglycan chain.
| Catalog Number | A000291 |
| CAS Number | 1404-93-9 |
| Synonyms | NA |
| Molecular Formula | C66H75Cl2N9O24 • XHCl |
| Purity | ≥95% |
| Target | Antibiotic |
| Solubility | Limited solubility |
| Storage | 3 years -20C powder |
| InChIKey | LCTORFDMHNKUSG-XTTLPDOESA-N |
| Reference | <p>Courvalin, Patrice. /Vancomycin Resistance in Gram-Positive Cocci./ <em>Oxford Journals</em>(2006): 25-34. <em>Clinical Infectious Diseaes</em>. Web. 21 Aug. 2012.</p><p>Pollock, H.M., Holt J., and Murray C., Comparison of susceptibilities of anaerobic bacteria to cefemenoxime, ceftriaxone and other antimicrobial compounds, Antimicrob. Agents Chemother., Vol. 23, pp.780-783, 1983</p><p>Silva J.A. and Fukai S., The impact of carbenicillin, cefotaxime and vancomycin on chrysanthemum and tobacco TCL morphogenesis and Agrobacterium growth, J. Appl. Hort., Vol. 3(1), pp. 3-12, 2001.</p><p>Joshi, S., Ray, P., Manchanda, V., Bajaj, J., Chitnis, D. S., Gautam, V., &…Balaji, V. (2013). Methicillin resistant <em>Staphylococcus aureus</em> (MRSA) in India: Prevalence & susceptibility pattern. <em>Indian Journal Of Medical Research</em>, 137(2), 363-369</p></span></p> |
