Vanin-1-IN-3

• CAT Number: I043617
• CAS Number: 2940964-70-3
• Molecular Formula: C17H22F3NO5
• Molecular Weight: 377.36
• Purity: ≥95%
• Synonyms: (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-4-[4-(trifluoromethoxy)phenyl]butyl]butanamide
• InChI: InChI=1S/C17H22F3NO5/c1-16(2,10-22)14(24)15(25)21-8-7-12(23)9-11-3-5-13(6-4-11)26-17(18,19)20/h3-6,14,22,24H,7-10H2,1-2H3,(H,21,25)/t14-/m0/s1
• InChIKey: RSTKBZUZEJDDPA-AWEZNQCLSA-N
• SMILES: CC(C)(CO)[C@H](C(=O)NCCC(=O)CC1=CC=C(C=C1)OC(F)(F)F)O

Vanin-1-IN-3（Cat No.:I043617）is a selective small-molecule inhibitor of Vanin-1, a glycosylated protein involved in various biological processes, including oxidative stress and inflammation. Vanin-1 regulates the production of pantetheine, a precursor to coenzyme A, and plays a role in immune cell activation and tissue damage. By inhibiting Vanin-1, Vanin-1-IN-3 aims to reduce inflammation and tissue injury associated with conditions like cardiovascular diseases, neurodegeneration, and inflammatory disorders. Preclinical studies suggest that targeting Vanin-1 could be a promising therapeutic strategy to mitigate oxidative stress and improve outcomes in these diseases.