For research use only. Not for therapeutic Use.
Vanzacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) for researching cystic fibrosis.
| Catalog Number | I045090 |
| CAS Number | 2374124-49-7 |
| Synonyms | (14S)-8-[3-(2-dispiro[2.0.24.13]heptan-7-ylethoxy)pyrazol-1-yl]-12,12-dimethyl-2,2-dioxo-2λ6-thia-3,9,11,18,23-pentazatetracyclo[17.3.1.111,14.05,10]tetracosa-1(22),5(10),6,8,19(23),20-hexaen-4-one |
| Molecular Formula | C32H39N7O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C32H39N7O4S/c1-30(2)19-21-5-4-16-33-24-6-3-7-27(34-24)44(41,42)37-29(40)22-8-9-25(35-28(22)38(30)20-21)39-17-10-26(36-39)43-18-11-23-31(12-13-31)32(23)14-15-32/h3,6-10,17,21,23H,4-5,11-16,18-20H2,1-2H3,(H,33,34)(H,37,40)/t21-/m0/s1 |
| InChIKey | VCSUIBJKYCVWNF-NRFANRHFSA-N |
| SMILES | CC1(CC2CCCNC3=NC(=CC=C3)S(=O)(=O)NC(=O)C4=C(N1C2)N=C(C=C4)N5C=CC(=N5)OCCC6C7(C68CC8)CC7)C |
| Reference | [1]. Anderson CD, et al. Modulators of cystic fibrosis transmembrane conductance regulator. WO2021030555 A1. |
