For research use only. Not for therapeutic Use.
Vardenafil-d5 is a deuterated form of vardenafil, a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction. In this compound, five hydrogen atoms are replaced with deuterium, which enhances its use in pharmacokinetic studies by allowing for precise tracking and analysis in mass spectrometry and NMR spectroscopy. The deuterium labeling does not alter the drug’s pharmacological activity, making vardenafil-d5 valuable for studying the metabolism, distribution, and excretion of vardenafil in biological systems while retaining its therapeutic properties.
| Catalog Number | R005773 |
| CAS Number | 1189685-70-8 |
| Synonyms | 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-(ethyl-d5)-piperazine; Levitra-d5; Nuviva-d5; |
| Molecular Formula | C23H32N6O4S |
| Purity | ≥95% |
| Target | Phosphodiesterase (PDE) |
| Storage | -20°C |
| IUPAC Name | 2-[2-ethoxy-5-[4-(1,1,2,2,2-pentadeuterioethyl)piperazin-1-yl]sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one |
| InChI | InChI=1S/C23H32N6O4S/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30)/i2D3,6D2 |
| InChIKey | SECKRCOLJRRGGV-QKLSXCJMSA-N |
| SMILES | CCCC1=NC(=C2N1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C |
