Vardenafil hydrochloride

• CAT Number: I002730
• CAS Number: 224785-91-5
• Molecular Formula: C23H33ClN6O4S
• Molecular Weight: 525.06
• Purity: ≥95%
• Target: Phosphodiesterase (PDE)
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one;hydrochloride
• InChI: InChI=1S/C23H32N6O4S.ClH/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H
• InChIKey: XCMULUAPJXCOHI-UHFFFAOYSA-N
• SMILES: CCCC1=NC(=C2N1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C.Cl

Vardenafil hydrochloride (Cat.No:I002730) is a medication used to treat erectile dysfunction (ED) in men. It belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors, which increase blood flow to the penis, facilitating and maintaining erections. Vardenafil hydrochloride is commonly marketed under the brand name Levitra and has demonstrated effectiveness in improving sexual performance.

Reference

[1]. Saenz de Tejada, I., et al., The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. Int J Impot Res, 2001. 13(5): p. 282-90.
[2]. Goldstein, I., et al., Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind placebo-controlled fixed-dose study. Diabetes Care, 2003. 26(3): p. 777-83.