Varenicline-d4 hydrochloride

• CAT Number: S000465
• Molecular Formula: C13H9D4N3.xHCl
• Purity: ≥95%
• IUPAC Name: 13,13,15,15-tetradeuterio-5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene;hydrochloride
• InChI: InChI=1S/C13H13N3.ClH/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1;/h1-2,4-5,8-9,14H,3,6-7H2;1H/i6D2,7D2
• InChIKey: ZUCZFANFKYSVKF-FEUVXQGESA-N
• SMILES: C1C2CNCC1C3=CC4=NC=CN=C4C=C23.Cl

Varenicline-d4 hydrochloride（Cat No.:S000465） is a deuterated form of varenicline hydrochloride, where four hydrogen atoms are replaced with deuterium. Varenicline, marketed as Chantix, is a medication primarily used to aid smoking cessation by acting as a partial agonist at nicotinic acetylcholine receptors, reducing craving and withdrawal symptoms. The inclusion of deuterium in Varenicline-d4 hydrochloride enhances the compound’s metabolic stability, making it valuable for detailed pharmacokinetic and metabolic research.