VB124

• CAT Number: I047515
• CAS Number: 2230186-18-0
• Molecular Formula: C23H23ClN2O4
• Molecular Weight: 426.89
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CC(C)(OCC1=N[N](C2=C(Cl)C=CC=C2)C(=C1)C3=CC(=CC=C3)OC4CC4)C(O)=O

VB124, a potent and selective MCT4 inhibitor, specifically inhibits lactate efflux/import in MDA-MB-231 cells expressing MCT4, and is used for the research of cardiac hypertrophy, heart failure, and metabolism.

Reference

[1] Cluntun AA, et al. Cell Metab. 2021;33(3):629-648.e10.
[2] Cluntun AA, et al. Cell Metab. 2021 Mar 2;33(3):629-648.e10.