VBIT-12

• CAT Number: I037977
• CAS Number: 2089227-65-4
• Molecular Formula: C25H27N3O3
• Molecular Weight: 417.5
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: C1CN(CCC1(C(=O)NCC(=O)O)NC2=CC=CC=C2)CC3=CC=CC4=CC=CC=C43

VBIT-12 is a potent inhibitor of Voltage-dependent anion-selective channel 1 (VDAC1), directly interacting with purified VDAC1, reducing its channel conductance and preventing VDAC1 oligomerization.

Reference

[1] Shoshan-Barmatz, et al. US 2020/0000801 A1.
[2] Shoshan-Barmatz V, et al. Pharmacol Res. 2018 May;131:87-101.