For research use only. Not for therapeutic Use.
VEGFR-2-IN-37(CAT: I040342) is a potent and selective small-molecule inhibitor targeting Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2), a key mediator of angiogenesis in cancer and other pathological conditions. By blocking VEGFR-2 kinase activity, this inhibitor disrupts VEGF-induced signal transduction, effectively suppressing endothelial cell proliferation, migration, and new blood vessel formation. VEGFR-2-IN-37 is valuable for studying tumor vascularization, metastasis, and anti-angiogenic therapeutic strategies. Its high specificity makes it a reliable tool in preclinical oncology models and vascular biology assays. Suitable for in vitro and in vivo research exploring angiogenesis inhibition and vascular-targeted drug development.
| CAS Number | 298207-77-9 |
| Synonyms | 1-[3-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yloxy)phenyl]ethanone |
| Molecular Formula | C18H16N2O2S |
| Purity | ≥95% |
| IUPAC Name | 1-[3-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yloxy)phenyl]ethanone |
| InChI | InChI=1S/C18H16N2O2S/c1-11(21)12-5-4-6-13(9-12)22-17-16-14-7-2-3-8-15(14)23-18(16)20-10-19-17/h4-6,9-10H,2-3,7-8H2,1H3 |
| InChIKey | STAQHFQLHGDVFW-UHFFFAOYSA-N |
| SMILES | CC(=O)C1=CC(=CC=C1)OC2=C3C4=C(CCCC4)SC3=NC=N2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
