For research use only. Not for therapeutic Use.
Velaresol (BW 12C) is a potent left-shifting anti-sickling compound in vitro[1]. Sickle cell disease is an inherited disorder of the hemoglobin molecule. When hemoglobin molecules are exposed to a variety of environments, the red blood cell hemoglobin polymerizes, twists, and morphs into a sickle shape.
| Catalog Number | I009535 |
| CAS Number | 77858-21-0 |
| Synonyms | 5-(2-formyl-3-hydroxyphenoxy)pentanoic acid |
| Molecular Formula | C12H14O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H14O5/c13-8-9-10(14)4-3-5-11(9)17-7-2-1-6-12(15)16/h3-5,8,14H,1-2,6-7H2,(H,15,16) |
| InChIKey | NSUDGNLOXMLAEB-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)OCCCCC(=O)O)C=O)O |
| Reference | [1]. Fitzharris P, et al. The effects in volunteers of BW12C, a compound designed to left-shift the blood-oxygen saturation curve. Br J Clin Pharmacol. 1985 Apr;19(4):471-81. |
