For research use only. Not for therapeutic Use.
(-)-Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-)-Vesamicol can be used for release and recycling of synaptic vesicles study[1].
| Catalog Number | M030383 |
| CAS Number | 112709-59-8 |
| Synonyms | (1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol |
| Molecular Formula | C17H25NO |
| Purity | ≥95% |
| InChI | InChI=1S/C17H25NO/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14/h1-3,6-7,15-17,19H,4-5,8-13H2/t16-,17-/m1/s1 |
| InChIKey | YSSBJODGIYRAMI-IAGOWNOFSA-N |
| SMILES | C1CCC(C(C1)N2CCC(CC2)C3=CC=CC=C3)O |
| Reference | [1]. Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116. |
