VGX-1027

• CAT Number: I004453
• CAS Number: 6501-72-0
• Molecular Formula: C11H11NO3
• Molecular Weight: 205.20
• Purity: ≥95%
• Synonyms: VGX-1027
• Target: Apoptosis
• Solubility: DMSO: ≥ 56 mg/mL
• Storage: 2-8°C
• IUPAC Name: 2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid
• InChI: InChI=1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)
• InChIKey: MUFJHYRCIHHATF-UHFFFAOYSA-N
• SMILES: C1C(ON=C1C2=CC=CC=C2)CC(=O)O

VGX-1027（Cat No.:I004453）, also known as GIT27, is an isoxazole compound with potent immunomodulatory properties. This compound has been shown to reduce the secretion of inflammatory cytokines, such as IL-1beta, TNF-alpha, and IL-10, from purified murine macrophages. By modulating the immune response, VGX-1027 has the potential to regulate inflammation and immune-mediated diseases. Its ability to inhibit cytokine production suggests its potential as a therapeutic agent for conditions characterized by excessive inflammation.