Vidarabine monohydrate

• CAT Number: I016772
• CAS Number: 24356-66-9
• Molecular Formula: C₁₀H₁₅N₅O₅
• Molecular Weight: 285.26
• Purity: ≥95%
• Target: HSV
• Storage: Room temperature
• IUPAC Name: (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;hydrate
• InChI: InChI=1S/C10H13N5O4.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10;/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13);1H2/t4-,6-,7+,10-;/m1./s1
• InChIKey: ZTHWFVSEMLMLKT-CAMOTBBTSA-N
• SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N.O

Vidarabine monohydrate（Cat No.:I016772）, also known as adenine arabinoside, is an antiviral drug with activity against herpes simplex viruses (HSV) and varicella-zoster viruses. It works by inhibiting viral DNA replication through the incorporation of arabinose nucleotides into the viral DNA chain, leading to the termination of viral synthesis. Vidarabine monohydrate is primarily used in the treatment of herpes infections, including herpes simplex keratitis and herpes zoster ophthalmicus. Its antiviral properties and effectiveness against these viruses make it a valuable therapeutic option in managing these viral infections.

Reference

[1]. Whitley, R., et al., Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs, 1980. 20(4): p. 267-82.