For research use only. Not for therapeutic Use.
viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells. viFSP1 targets the highly conserved NAD(P)H binding pocket of FSP1 and directly inhibits FSP1. viFSP1 induces lipid peroxidation and has anticancer activity[1].
| Catalog Number | I040511 |
| CAS Number | 951945-67-8 |
| Synonyms | 1-(2,4-dimethoxyphenyl)-5-imino-4-(4-methyl-1,3-thiazol-2-yl)-2H-pyrrol-3-ol |
| Molecular Formula | C16H17N3O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C16H17N3O3S/c1-9-8-23-16(18-9)14-12(20)7-19(15(14)17)11-5-4-10(21-2)6-13(11)22-3/h4-6,8,17,20H,7H2,1-3H3 |
| InChIKey | WIFWMPYWKNDQSJ-UHFFFAOYSA-N |
| SMILES | CC1=CSC(=N1)C2=C(CN(C2=N)C3=C(C=C(C=C3)OC)OC)O |
| Reference | [1]. Nakamura T et al. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation. Nat Struct Mol Biol. 2023 Nov;30(11):1806-1815. |
