Vildagliptin β-D-Glucuronide

• CAT Number: R011516
• CAS Number: 1147403-03-9
• Molecular Formula: C23H33N3O8
• Molecular Weight: 479.53
• Purity: ≥95%
• Synonyms: (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile?O-β-D-Glucopyranosiduronic Acid; Vildagliptin O-Glucuronide
• Storage: Desiccate at RT
• IUPAC Name: (2S,3S,4S,5R,6S)-6-[[(5S,7R)-3-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]-1-adamantyl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• InChI: InChI=1S/C23H33N3O8/c24-9-14-2-1-3-26(14)15(27)10-25-22-5-12-4-13(6-22)8-23(7-12,11-22)34-21-18(30)16(28)17(29)19(33-21)20(31)32/h12-14,16-19,21,25,28-30H,1-8,10-11H2,(H,31,32)/t12-,13+,14-,16-,17-,18+,19-,21-,22?,23?/m0/s1
• InChIKey: PSIDBGKCTWXOHS-BADMEQAASA-N
• SMILES: C1CC(N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)OC5C(C(C(C(O5)C(=O)O)O)O)O)C#N

Vildagliptin β-D-Glucuronide is a metabolite of the dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin, used in pharmaceutical research. It is crucial for studying the pharmacokinetics, pharmacodynamics, and metabolic pathways of vildagliptin. This compound aids in understanding the drug’s mechanism of action, therapeutic efficacy, and safety profile. Researchers rely on Vildagliptin β-D-Glucuronide for precise and reliable results in advanced diabetes research and drug development, contributing significantly to innovations in the treatment of type 2 diabetes and related metabolic disorders.