Vildagliptin-d3

• CAT Number: R011514
• CAS Number: 1217546-82-1
• Molecular Formula: C17H25N3O2
• Molecular Weight: 306.424
• Purity: ≥95%
• Synonyms: (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-(pyrrolidine-d3)carbonitrile; LAF 237-d3; NVP-LAF 237-d3; Galvus-d3
• Storage: Desiccate at RT
• IUPAC Name: (2S)-2,5,5-trideuterio-1-[2-[[(5S,7R)-3-hydroxy-1-adamantyl]amino]acetyl]pyrrolidine-2-carbonitrile
• InChI: InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12-,13+,14-,16?,17?/m0/s1/i3D2,14D
• InChIKey: SYOKIDBDQMKNDQ-COZVPQRFSA-N
• SMILES: [2H][C@]1(CCC(N1C(=O)CNC23C[C@H]4C[C@@H](C2)CC(C4)(C3)O)([2H])[2H])C#N

Vildagliptin-d3 is a deuterated form of vildagliptin, an oral antidiabetic drug used to manage type 2 diabetes by inhibiting the enzyme DPP-4 (dipeptidyl peptidase-4). In this compound, three hydrogen atoms are replaced with deuterium. It functions as an internal standard in mass spectrometry and NMR spectroscopy, improving the accuracy of quantification and structural analysis. In pharmaceutical chemistry, it supports studies on drug metabolism, pharmacokinetics, and pharmacodynamics. Its deuterium labeling ensures precise measurements and reliable data in research and development, particularly in drug efficacy and safety evaluations.